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"Life Sciences International Postgraduate Educational Center would be developed as a regional education and research center serving to promote co-operation between scientists and to facilitate the exchange of information among researchers internationally".
Federico Mayor Ex-Director General of UNESCO
 
MODERN PROBLEMS OF CELLULAR & MOLECULAR BIOPHYSICS
Edited by: Sinerik N. Ayrapetyan (Armenia)
Anthony C. T. North (UK)
Volume: 362 pages
Price: $25
This volume represents a collection of selected reviews on modern approaches and newest achievements in various fields of cellular and molecular life sciences presented by distinguished scientists from different countries in recent UNESCO seminars organized by LSIEC in collaboration with IBRO, IUPAB and WHO.

The papers do indeed cover a very wide range, both of subject matter and of the level of sophistication of the methods used to obtain the results described. Part I, Cellular Biophysics, contains a number of topics in membrane biophysics, including the regulation of ion transport across cell membranes; the effects of ions, hormones and other metabolites on neural mechanisms; the biochemical processes that underlie the mechanisms of learning and memory; intracellular and intercellular signaling mechanisms. In Part II, Molecular Biophysics, there are chapters on crystallographic, spectroscopic and electron microscopic methods for studying biomolecular structure and organization; on theoretical and computer-based methods for studying molecular conformation, protein/ligand and nucleic acid/ligand interactions and conformational changes in solution and the solid state; and molecular evolution.

This volume can be used as a guidebook for life sciences departments? students at the universities and young scientists, as well as adult researchers interested in modern problems in the fields of life sciences presented in the book.
TABLE OF CONTENTS
PART I. CELLULAR BIOPHYSICS

1 Application of Gramicidin Perforated Patch Recording Technique to Various Cells
Norio Akaike (Japan)

2 Calcium Signaling in Neuronal Cells: Mechanisms and Function
Platon G. Kostyuk (Ukraine)

3 Na-K Pump and Na:Ca Exchanger as Metabolic Regulators and Sensors for Extraweak Signals in Neuromembrane
Sinerik N. Ayrapetyan (Armenia)

4 Parathyroid Hormone as a Regulator of Functional Activity of Neuron
Anna S. Ter-Markosyan and Drastamat N. Khudaverdyan (Armenia)

5 Participation of Second Messengers in Decrease of Cholinosensitivity of Command Helix Neurons in Cellular Model of Habituation. Modulatory Effects of Opioids
Arkady S. Pivovarov (Russia)

6 Long-term Potentiation and Long-term Depression: Relevance to Learning and Memory
David O. Carpenter, Rifat Hussain, Yuasheng Tan, William Niemi, and Nobuaki Hori (USA-Japan)

7 Cardiac Sensory Receptors and Their Reflex Regulatory Function
Mohammed Fahim (India)

8 Biomedical Applications of Biogenic and Biocompatible Magnetic Nanoparticles
Jon Dobson, Brooks Gross, Chris Exley, Albina Michailovina, Christopher Batich, and Heath Pardoe (UK-USA)

9 The Possible Role of Dehydrating Effect of Static Magnetic Fields in Cancer Treatment
Armine A. Danielyan (Armenia)

10 Endothelial Function in Cardiovascular Diseases: Perspectives of Primary Prevention
Gaiane Simonia (Georgia)

11 Differential Interference Contrast Microscopy: Characteristics and Application in Studies of Living Cells
Susumu Terakawa (Japan)

12 Assessing Cytoplasmic Water Deficit in Cyanobacteria with Chlorophyll Fluorescence
George C. Papageorgiou (Greece)

PART II. MOLECULAR BIOPHYSICS

1 Structural Molecular Biology
Anthony C. T. North (UK)

2 Molecular spectroscopy of upper excited electronic states of porphyrins
Gagik G. Gurzadyan, Thu-Hoa Tran-Thi, and Thomas Gustavsson (Armenia-France)

3 Some Dynamic Properties of Random Heteropolymers with Correlations in Sequence
Eugene Sh. Mamasakhlisov, Yeva B. Dalyan, and Vladimir F. Morozov (Armenia)

4 The Microscopic Theory of Helix-Coil Transition in One- and Double-Strand Biopolymers
Vladimir F. Morozov, Eugene Sh. Mamasakhlisov, Nerses S. Ananikyan, Shura A. Hairyan (Armenia)

5 Structure and Evolution of RNA
Paul G. Higgs (UK)

6 Conformational Transition of DNA and DNA-Ligand Complexes: Thermodynamic Parameters as Revealed By The Theory – Experiment Comparison
Armen T. Karapetian, Andranik M. Muradian, Genady A. Terzikian and Poghos O. Vardevanian (Armenia)

7 Biological and thermodynamic properties of DNA cross-linked by anticancer drugs
Dmitri Y. Lando, Alexander S. Fridman, Albert S. Benight, and Samvel G. Haroutiunian

8 Structural transfers and stability of DNA and polynucleotides at the presence of low molecular ligands (metal ions, aminoacids, antitumoral preparations)
Samvel G. Haroutiunian, Yeva B. Dalyan, Eugenie Sh. Mamasakhlisov, and Dmitri Yu. Lando (Armenia - Belarus)

9 HIV Fusion Strategy at the Molecular Level
Nuno C. Santos and Miguel A. R. B. Castanho (Portugal)

10 Computer-aided techniques for the ultrastructural study of a protein
Margaret Tzaphlidou (Greece)

11 The Xcollagen Fibril – A Model System for Studying Structural Properties, as well as Staining and Fixation of a Protein
Margaret Tzaphlidou (Greece)

12 Molecular Physiology of K+ Channels
Yaroslav M. Shuba (Ukraine)

13 Stochastic Description of Particles Adsorption on the Membrane
Valeri B. Arakelyan and Hakob V. Arakelyan (Armenia)
BIOPHYS-EXPERT-1
Description: The device “Biophys-Expert-1” is designed for measurement of active and reactive (capacitive) components of electrical conductivity of biotissues in two-frequency mode, in micropower regime. The device also provides the measurement of the temperature in the area of conductivity measurement.

Technical Parameters
- Diapason of conductivity measurement 10-5 – 10-3 S
- Precision of conductivity measurement ± 0,8 %
- Diapason of temperature measurement 0 – 50 0C
- Precision of temperature measurement ± 0,1 0C
- Frequency of measurement HF 1580±1 Hz
- Frequency of measurement LF 17,5±02 Hz
- Voltage 35 x 10-3 V
- Form of measuring current sinusoidal
- Power of self-heating during conductivity measurement ≤ 0,612 x 10-6 W
- Power of self-heating during temperature measurement ≤ 2,73 x 10-6 W
- Form of conductivity sensor radial placed electrodes
- Form of temperature sensor needle-shaped
- Diameter of temperature sensor 0,9 mm
- Charge of built-in digital voltmeter 3,5
- Power supply (autonomous) 9± 2 V
- Expendable current 72±3 mA
- Operation duration of the storage battery with capacity of 180mA/h 2,2 hours
- HWD 120 x 213 x 85
- Weigh 1,2 kg
Price: $2999
 
BIOPHYS-01
Description: Multifunction device for the investigation of living cells by microelectrode with ease of operation and wide capabilities:

- Investigations with the help of voltage clamp on cell membrane
- Capability for iontoforetic influence
- High resistance input for connecting the ion-selective electrode.
- Internal isolated source for stimulating voltage.
- Capability of measuring the resistance of microelectrode
- Outputs for connecting the external outputs
Price: $1499
 
BIOPHYS TT-01
Description: THERMOMETER AND THERMOSTAT

A device for imitation of the thermal processes. It provides a high precision tracking of the temperature in the Chamber of temperature measurements. The device has unique capabilities for studying the thermal processes.

Technical parameters:
- Diapason of the measuring temperature – 100 - + 100 0C
- Precision of the temperature measurement ± 0,3 0C
- Allowable capacity – 0,1 0C; 0,01 0C
- The rate of the setting of the temperature in the Chamber - 0,8 sec.
- The diameter of the thermo sensor – 0,83 mm
Price: $2199